The cerebral response to sodium nitroprusside and trimethaphan controlled hypotension
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چکیده
منابع مشابه
The cerebral response to sodium nitroprusside and trimethaphan controlled hypotension.
THE EFFECTS of altered arterial blood pressure on cerebral blood flow ( CBF ) have been well documented by Lassen 1'2 and Olesen 3 in man, and by Rapela, 4 Waltz ~ and Yashon 6 in dogs. The critical determinants of cerebral blood flow are the cerebral perfusion pressure (CPP) and the cerebrovascular resistance (CVR). The CPP is the difference between the driving force of the mean arterial press...
متن کاملCerebrovascular response to carbon dioxide during sodium nitroprusside- and isoflurane-induced hypotension.
We have examined the cerebrovascular response to carbon dioxide during normotension, sodium nitroprusside (SNP)-induced hypotension and high dose isoflurane-induced hypotension in 10 patients who received a standardized general anaesthetic. Carbon dioxide reactivity was determined by varying PaCO2 between 3.0 and 8.0 kPa and recording simultaneously blood flow velocity from the middle cerebral ...
متن کاملCerebral blood flow and metabolism during hypotension induced with sodium nitroprusside.
Cerebral blood flow and metabolism have been studied in 11 patients during general anaesthesia and hypotension induced with sodium nitroprusside in combination with captopril. Cerebral blood flow was measured, using a Novo Cerebrograph model 10A, after injection of 133 xenon into an arm vein. Arterial and venous blood samples were drawn to calculate cerebral metabolism. Captopril 1 mg.kg-1 oral...
متن کاملMetabolic effects of induced hypotension with trimetaphan and sodium nitroprusside.
In two groups of patients undergoing induced hypotension with sodium nitroprusside or trimetaphan blood concentrations of lactate, pyruvate and standard bicarbonate did not differ significantly between the groups. In the nine patients who received trimetaphan there was a progressive, but statistically non-significant, decrease in mean lactate. Nitroprusside (15 patients) was associated with a s...
متن کاملCentral and Regional Haemodynamics during Controlled Hypotension Produced by Adenosine, Sodium Nitroprusside and Nitroglycerin
Induced hypotension during anaesthesia was introduced by Gardner in 1946 [1]. Reasons for the use of deliberate hypotension during surgery are to facilitate the surgery and to decrease blood loss [2]. However, in a retrospective series [3] there was an overall incidence of complications of more than 3%, and there is always a risk of underperfusion of vital organs—a hazard that the anaesthetist ...
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ژورنال
عنوان ژورنال: Canadian Anaesthetists’ Society Journal
سال: 1975
ISSN: 0008-2856,1496-8975
DOI: 10.1007/bf03004869